Description: Homo sapiens FK506 binding protein 7 (FKBP7), transcript variant 1, mRNA. RefSeq Summary (NM_181342): The protein encoded by this gene belongs to the FKBP-type peptidyl-prolyl cis/trans isomerase (PPIase) family. Members of this family exhibit PPIase activity and function as molecular chaperones. A similar protein in mouse is located in the endoplasmic reticulum and binds calcium. [provided by RefSeq, Jul 2008]. Transcript (Including UTRs) Position: hg19 chr2:179,328,391-179,343,355 Size: 14,965 Total Exon Count: 4 Strand: - Coding Region Position: hg19 chr2:179,330,497-179,343,226 Size: 12,730 Coding Exon Count: 4
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
Pfam Domains: PF00254 - FKBP-type peptidyl-prolyl cis-trans isomerase PF13202 - EF hand PF13499 - EF-hand domain pair
ModBase Predicted Comparative 3D Structure on Q9Y680-2
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Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.