Human Gene IFI27 (uc021sba.1)
Description: Homo sapiens interferon, alpha-inducible protein 27 (IFI27), transcript variant 2, mRNA.
Transcript (Including UTRs)
Position: hg19 chr14:94,577,079-94,583,033 Size: 5,955 Total Exon Count: 5 Strand: +
Coding Region
Position: hg19 chr14:94,578,029-94,582,864 Size: 4,836 Coding Exon Count: 4
Data last updated at UCSC: 2013-06-14
Sequence and Links to Tools and Databases
Primer design for this transcript
Genetic Association Studies of Complex Diseases and Disorders
Genetic Association Database (archive): IFI27
CDC HuGE Published Literature: IFI27
MalaCards Disease Associations
Comparative Toxicogenomics Database (CTD)
Common Gene Haplotype Alleles
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RNA-Seq Expression Data from GTEx (53 Tissues, 570 Donors)
Microarray Expression Data
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mRNA Secondary Structure of 3' and 5' UTRs
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
Protein Domain and Structure Information
InterPro Domains: Graphical view of domain structure IPR009311 - Interferon-induced_6-16
Pfam Domains: PF06140 - Interferon-induced 6-16 family
ModBase Predicted Comparative 3D Structure on A8K0H0
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
Gene Ontology (GO) Annotations with Structured Vocabulary
Descriptions from all associated GenBank mRNAs
LF384883 - JP 2014500723-A/192386: Polycomb-Associated Non-Coding RNAs.AK289535 - Homo sapiens cDNA FLJ78595 complete cds, highly similar to Homo sapiens interferon, alpha-inducible protein 27 (IFI27), mRNA.AK097084 - Homo sapiens cDNA FLJ39765 fis, clone SPLEN2000222.AK312089 - Homo sapiens cDNA, FLJ92370, highly similar to Homo sapiens interferon, alpha-inducible protein 27 (IFI27), mRNA.BX647330 - Homo sapiens mRNA; cDNA DKFZp686F05171 (from clone DKFZp686F05171).AJ294851 - Homo sapiens partial mRNA for ISG12 protein (p27 gene).AY126456 - Homo sapiens interferon-induced ISG12c delta isoform (ISG12) mRNA, partial cds; alternatively spliced.AY126457 - Homo sapiens interferon-induced ISG12-S short isoform (ISG12) mRNA, partial cds; alternatively spliced.AY126458 - Homo sapiens interferon-induced ISG12-S short isoform (ISG12) mRNA, partial cds; alternatively spliced.BC015492 - Homo sapiens interferon, alpha-inducible protein 27, mRNA (cDNA clone MGC:8967 IMAGE:3915505), complete cds.X67325 - Homo sapiens mRNA for ISG12 protein.KJ891426 - Synthetic construct Homo sapiens clone ccsbBroadEn_00820 IFI27 gene, encodes complete protein.AB463793 - Synthetic construct DNA, clone: pF1KB8359, Homo sapiens IFI27 gene for interferon, alpha-inducible protein 27, without stop codon, in Flexi system.AM393107 - Synthetic construct Homo sapiens clone IMAGE:100002549 for hypothetical protein (IFI27 gene).AM393779 - Synthetic construct Homo sapiens clone IMAGE:100002567 for hypothetical protein (IFI27 gene).DQ893816 - Synthetic construct Homo sapiens clone IMAGE:100008276; FLH164681.01L; RZPDo839A08157D interferon, alpha-inducible protein 27 (IFI27) gene, encodes complete protein.BT006781 - Homo sapiens interferon, alpha-inducible protein 27 mRNA, complete cds.LC420312 - Homo sapiens IFI27 mRNA for interferon alpha-inducible protein 27, complete cds.AK095039 - Homo sapiens cDNA FLJ37720 fis, clone BRHIP2019149, moderately similar to Interferon, alpha-inducible protein 27.JD151797 - Sequence 132821 from Patent EP1572962.JD323154 - Sequence 304178 from Patent EP1572962.MA620460 - JP 2018138019-A/192386: Polycomb-Associated Non-Coding RNAs.
Other Names for This Gene
Alternate Gene Symbols: A8K0H0, A8K0H0_HUMAN, hCG_22330, NM_001130080, NP_001123552UCSC ID: uc021sba.1RefSeq Accession: NM_001130080
Protein: A8K0H0
CCDS: CCDS32148.1
Gene Model Information
category:
coding
nonsense-mediated-decay:
no
RNA accession:
NM_001130080.1
exon count:
5 CDS single in 3' UTR:
no
RNA size:
665
ORF size:
360 CDS single in intron:
no
Alignment % ID:
100.00
txCdsPredict score:
920.00 frame shift in genome:
no
% Coverage:
97.44
has start codon:
yes
stop codon in genome:
no
# of Alignments:
1
has end codon:
yes
retained intron:
no
# AT/AC introns
0
selenocysteine:
no
end bleed into intron:
0 # strange splices:
0
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Methods, Credits, and Use Restrictions
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