Human Gene SNCG (ENST00000372017.4) from GENCODE V38
Description: Homo sapiens synuclein gamma (SNCG), transcript variant 1, mRNA. (from RefSeq NM_003087) RefSeq Summary (NM_003087): This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010]. Gencode Transcript: ENST00000372017.4 Gencode Gene: ENSG00000173267.14 Transcript (Including UTRs) Position: hg38 chr10:86,958,599-86,963,258 Size: 4,660 Total Exon Count: 5 Strand: + Coding Region Position: hg38 chr10:86,958,698-86,962,985 Size: 4,288 Coding Exon Count: 5
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q6FHG5
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.