S. cerevisiae Gene MDM31 (YHR194W) Description and Page Index
  Description: Mitochondrial inner membrane protein with similarity to Mdm32p, required for normal mitochondrial morphology and inheritance interacts genetically with MMM1, MDM10, MDM12, and MDM34
Transcript (Including UTRs)
   Position: sacCer3 chrVIII:488,657-490,396 Size: 1,740 Total Exon Count: 1 Strand: +
Coding Region
   Position: sacCer3 chrVIII:488,657-490,396 Size: 1,740 Coding Exon Count: 1 

Page IndexSequence and LinksUniProtKB CommentsProtein StructureOther SpeciesGO Annotations
Other NamesMethods
Data last updated: 2011-08-29

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chrVIII:488,657-490,396)mRNAProtein (579 aa)
Gene SorterGenome BrowserOther Species FASTASGDUniProtKB

-  Comments and Description Text from UniProtKB
  ID: MDM31_YEAST
DESCRIPTION: RecName: Full=Mitochondrial distribution and morphology protein 31; Flags: Precursor;
FUNCTION: Involved in the organization of the mitochondrial membranes and the global structure of the mitochondria. Also required for mitochondrial distribution and mobility as well as for the maintenance of mitochondrial DNA nucleoids structures.
SUBUNIT: Interacts with MDM32. Participates in a complex of about 600 kDa.
SUBCELLULAR LOCATION: Mitochondrion inner membrane; Multi-pass membrane protein.
MISCELLANEOUS: Present with 1200 molecules/cell in log phase SD medium.
SIMILARITY: Belongs to the MDM31/MDM32 family.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR012571 - MDM31_MDM32_fun

Pfam Domains:
PF08118 - Yeast mitochondrial distribution and morphology (MDM) proteins

ModBase Predicted Comparative 3D Structure on P38880
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-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanMouseRatZebrafishD. melanogasterC. elegans
No orthologNo orthologNo orthologNo orthologNo orthologNo ortholog
      
      
      
      
      

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Molecular Function:
GO:0003674 molecular_function

Biological Process:
GO:0000001 mitochondrion inheritance
GO:0006873 cellular ion homeostasis
GO:0007005 mitochondrion organization
GO:1900208 regulation of cardiolipin metabolic process

Cellular Component:
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Other Names for This Gene
  UCSC ID: YHR194W
Protein: P38880 (aka MDM31_YEAST)

-  SGD Genes Methods, Credits, and Data Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.