Mouse Gene Slc25a21 (uc011ymc.1) Description and Page Index
  Description: mitochondrial 2-oxodicarboxylate carrier isoform
Transcript (Including UTRs)
   Position: mm9 chr12:57,813,621-58,261,630 Size: 448,010 Total Exon Count: 11 Strand: -
Coding Region
   Position: mm9 chr12:57,814,800-58,260,231 Size: 445,432 Coding Exon Count: 10 

Page IndexSequence and LinksUniProtKB CommentsCTDMicroarray ExpressionRNA Structure
Protein StructureOther SpeciesGO AnnotationsmRNA DescriptionsOther NamesModel Information
Methods
Data last updated: 2011-03-02

-  Sequence and Links to Tools and Databases
 
Genomic Sequence (chr12:57,813,621-58,261,630)mRNA (may differ from genome)Protein (305 aa)
Gene SorterGenome BrowserOther Species FASTAVisiGeneTable SchemaAllen Brain Atlas
BioGPSCGAPEnsemblEntrez GeneExonPrimerGeneCards
MGIPubMedStanford SOURCEUniProtKB

-  Comments and Description Text from UniProtKB
  ID: B6CI26_MOUSE
DESCRIPTION: SubName: Full=Mitochondrial 2-oxodicarboxylate carrier; SubName: Full=Mitochondrial solute carrier family 25 member 21;
SIMILARITY: Belongs to the mitochondrial carrier family.

-  Comparative Toxicogenomics Database (CTD)
  The following chemicals interact with this gene           more ... click here to view the complete list

-  Microarray Expression Data
 
Expression ratio colors:

GNF Expression Atlas 2 Data from GNF1M Mouse Chip

    
     
      
       
     
    
   
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GNF Expression Atlas Data from U74b Mouse Chip

          
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Absolute

-  mRNA Secondary Structure of 3' and 5' UTRs
 
RegionFold EnergyBasesEnergy/Base
Display As
5' UTR -11.4069-0.165 Picture PostScript Text
3' UTR -237.111179-0.201 Picture PostScript Text

The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.

-  Protein Domain and Structure Information
  InterPro Domains: Graphical view of domain structure
IPR018108 - Mitochondrial_sb/sol_carrier
IPR023395 - Mt_carrier_dom

Pfam Domains:
PF00153 - Mitochondrial carrier protein

SCOP Domains:
103506 - Mitochondrial carrier

ModBase Predicted Comparative 3D Structure on B6CI26
FrontTopSide
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.

-  Orthologous Genes in Other Species
  Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.
HumanRatZebrafishD. melanogasterC. elegansS. cerevisiae
Genome BrowserGenome BrowserNo orthologNo orthologNo orthologNo ortholog
Gene DetailsGene Details    
Gene SorterGene Sorter    
 RGD    
Protein SequenceProtein Sequence    
AlignmentAlignment    

-  Gene Ontology (GO) Annotations with Structured Vocabulary
  Cellular Component:
GO:0016020 membrane
GO:0016021 integral component of membrane


-  Descriptions from all associated GenBank mRNAs
  AK167535 - Mus musculus 14 days embryo liver cDNA, RIKEN full-length enriched library, clone:I530019A21 product:solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21, full insert sequence.
AK045180 - Mus musculus 9.5 days embryo parthenogenote cDNA, RIKEN full-length enriched library, clone:B130044A15 product:MOTOCHONDRIAL OXODICARBOXYLATE CARRIER homolog [Rattus norvegicus], full insert sequence.
AK041694 - Mus musculus 3 days neonate thymus cDNA, RIKEN full-length enriched library, clone:A630030I10 product:MOTOCHONDRIAL OXODICARBOXYLATE CARRIER homolog [Rattus norvegicus], full insert sequence.
AK162379 - Mus musculus adult male epididymis cDNA, RIKEN full-length enriched library, clone:9230119I19 product:solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21, full insert sequence.
AK036988 - Mus musculus adult female vagina cDNA, RIKEN full-length enriched library, clone:9930033G19 product:MOTOCHONDRIAL OXODICARBOXYLATE CARRIER homolog [Rattus norvegicus], full insert sequence.
EU180236 - Mus musculus mitochondrial solute carrier family 25 member 21 (Slc25a21) mRNA, complete cds, alternatively spliced; nuclear gene for mitochondrial product.
BC057980 - Mus musculus solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21, mRNA (cDNA clone MGC:67702 IMAGE:5042653), complete cds.
AK044945 - Mus musculus 9.5 days embryo parthenogenote cDNA, RIKEN full-length enriched library, clone:B130014P16 product:MOTOCHONDRIAL OXODICARBOXYLATE CARRIER homolog [Rattus norvegicus], full insert sequence.

-  Other Names for This Gene
  Alternate Gene Symbols: B6CI26, B6CI26_MOUSE, NM_001167976, NP_001161448, uc007npj.1
UCSC ID: uc011ymc.1
RefSeq Accession: NM_001167976
Protein: B6CI26 CCDS: CCDS49069.1

-  Gene Model Information
 
category: coding nonsense-mediated-decay: no RNA accession: NM_001167976.1
exon count: 11CDS single in 3' UTR: no RNA size: 2166
ORF size: 918CDS single in intron: no Alignment % ID: 100.00
txCdsPredict score: 1895.00frame shift in genome: no % Coverage: 100.00
has start codon: yes stop codon in genome: no # of Alignments: 1
has end codon: yes retained intron: no # AT/AC introns 0
selenocysteine: no end bleed into intron: 0# strange splices: 0
Click here for a detailed description of the fields of the table above.

-  Methods, Credits, and Use Restrictions
  Click here for details on how this gene model was made and data restrictions if any.