ID:TMM27_MOUSE DESCRIPTION: RecName: Full=Collectrin; AltName: Full=Transmembrane protein 27; Flags: Precursor; FUNCTION: Regulator of SNARE complex function. Stimulator of beta cell replication. SUBUNIT: Homodimer. Interacts with SNAPIN. Associates with SLC6A18. SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein (Potential). TISSUE SPECIFICITY: Kidney; collecting ducts. Pancreas; beta cells of islets. PTM: Glycosylated. PTM: The extracellular domain is cleaved and released from the cell membrane of pancreatic beta cells. SIMILARITY: Belongs to the TMEM27 family.
The RNAfold program from the Vienna RNA Package is used to perform the secondary structure predictions and folding calculations. The estimated folding energy is in kcal/mol. The more negative the energy, the more secondary structure the RNA is likely to have.
ModBase Predicted Comparative 3D Structure on Q9ESG4
The pictures above may be empty if there is no ModBase structure for the protein. The ModBase structure frequently covers just a fragment of the protein. You may be asked to log onto ModBase the first time you click on the pictures. It is simplest after logging in to just click on the picture again to get to the specific info on that model.
Orthologous Genes in Other Species
Orthologies between human, mouse, and rat are computed by taking the best BLASTP hit, and filtering out non-syntenic hits. For more distant species reciprocal-best BLASTP hits are used. Note that the absence of an ortholog in the table below may reflect incomplete annotations in the other species rather than a true absence of the orthologous gene.