Gene interactions and pathways from curated databases and text-mining

◀ Back to MTOR

MTOR — NA

Text-mined interactions from Literome

Chen et al., Lab Invest 2010 : N-acetyl-L-cysteine (NAC) , a scavenger of reactive oxygen species ( ROS ), blocked H ( 2 ) O ( 2 ) inhibition of mTOR signaling
Lai et al., Arthritis Rheum 2012 (Lupus Erythematosus, Systemic) : NAC increased d?m ( P = 0.0001 ) in all T cells, profoundly reduced mTOR activity ( P = 0.0009 ), enhanced apoptosis ( P = 0.0004 ), reversed expansion of CD4-CD8- T cells ( mean ± SEM 1.35 ± 0.12-fold change ; P = 0.008 ), stimulated FoxP3 expression in CD4+CD25+ T cells ( P = 0.045 ), and reduced anti-DNA production ( P = 0.049 )