Gene interactions and pathways from curated databases and text-mining
PTPN11: top 25 interacting genes (chr12:112856535-112947717)
Mouse over or click genes or lines for details. Dashed lines indicate interactions without text mining support. Click any gene to make it the new center. Click any line to show details about the interaction. Only PTPN11-interacting genes and only the most-mentioned/most-curated interactions are shown in the graph. See the Help Page for details.
Gene:               Hide non-PTPN11 interactions     Show top Genes on graph    

Less-frequently mentioned interactions with PTPN11, not among the Top 25
Other genes interacting with PTPN11. Mouse-over to show number of abstracts or databases. Sorted alphabetically (sort by article count).
Like above, interactions are colored by support. Grey:only text mining, light-blue:interaction database, blue:pathway database

A2M AARS ABCE1 ABL1 ABLIM1 ABLIM3 ACAT1
ACO2 ACR ACTA2 ACTB ACTBL2 ACTC1 ACTG1
ACTG2 ACTL7A ACTN1 ACTN4 ACTR2 ACTR3 ACVR2B
ADCY2 AGFG1 AGRN AIF1L AKT1 AKT1S1 AKT3
ALB ALDOA ALYREF ANG ANGPT1 ANGPT2 ANKAR
ANP32B ANXA1 ANXA2 ANXA6 AP2A1 AP2B1 AP2M1
AP2S1 APBA1 AQP2 ARAP1 ARCN1 ARF1 ARF5
ARHGAP1 ARPC1A ARPC2 ARPC3 ARPC4 ARPC5 ASAP1
ASF1A ASF1B ASNS ASPH ATAD3A ATP1A1 ATP5A1
ATP5C1 ATP5O ATP6V0D1 ATP6V1G2 AXIN1 AXL BCAR1
BCL10 BCL2 BCL3 BCL5 BCL6 BCL9 BCLAF1
BCR BDKRB2 BDNF BECN1 BHMT BIRC2 BIRC3
BIRC8 BOLA2 BOLA2B BPNT1 BRE BSND BTK
BTLA BYSL C6orf25 CAB39 CACYBP CAD CALB1
CALCOCO2 CALM1 CALU CAMK2D CANX CAPZA1 CAPZB
CASP1 CASP10 CASP12 CASP14 CASP16 CASP2 CASP3
CASP4 CASP5 CASP6 CASP7 CASP8 CASP9 CBL
CBLB CBR1 CCDC113 CCM2L CCT5 CD19 CD247
CD274 CD2AP CD33 CD3D CD3E CD3G CD3Z
CD4 CD59 CD79A CD79B CD80 CD84 CD86
CDC20 CDC73 CDCA8 CDH5 CDIPT CDKN1A CDX2
CEBPA CEP290 CFL1 CFL2 CFTR CHAF1B CHD4
CHRAC1 CHUK CKB CKM CKMT1A CKMT1B CLPX
CNBP CNOT1 CNST CNTF CNTNAP2 COL6A1 COL6A2
COPA CORO1A CORO1B CORO1C CPLX1 CPS1 CPSF7
CRB2 CRB3 CRISPLD2 CRK CRKL CSF1 CSF2
CSF2RA CSF2RB CSF3 CSF3R CSK CSNK1A1 CSNK1A1L
CSNK2B CTNNB1 CTNND1 CTR9 CTTN CXADR CXCL12
CXCR4 CYBB CYCS DAB1 DAPK3 DARS DBN1
DCC DCD DCTN1 DDAH1 DDOST DDX39B DDX3X
DDX42 DDX5 DDX6 DHX15 DHX9 DIMT1 DLD
DLST DNAJA1 DNAJA2 DNM1 DNM2 DNM3 DOK1
DPYSL2 DSG1 DSP DST DTD1 DUT DYNC1H1
DYNLL1 DZIP1 ECH1 EEF1A1 EEF1B2 EEF1E1 EEF1G
EEF2 EFHD2 EGFR EIF2AK2 EIF3B EIF4A1 EIF4A3
EIF4EBP1 EIF5A EIF6 EMD ENO1 ENO3 EPB41
EPN1 EPO EPOR EPPK1 EPS15 EPS8L1 ERBB2
ERBB3 ERBB4 ERC2 ERCC8 ERLIN1 EXOC1 EXOC4
F2 FADD FAM175B FAR1 FARSB FASN FBXO2
FCER1A FCER1G FCRL3 FERMT3 FGF1 FGF10 FGF11
FGF12 FGF13 FGF14 FGF16 FGF17 FGF18 FGF19
FGF2 FGF20 FGF21 FGF22 FGF23 FGF3 FGF4
FGF5 FGF6 FGF7 FGF8 FGF9 FGFR1 FGFR2
FGFR3 FGFR4 FH FKBP1A FKBP4 FLG2 FLII
FLNA FLNB FLNC FLOT1 FLT1 FLT3 FLT4
FNTB FOXO1 FOXP3 FRS2 FRS3 FSCN1 FUS
FYCO1 FYN GAB2 GAPDH GAS8 GATA2 GATAD2B
GCH1 GDF11 GDI1 GDI2 GEMIN2 GEMIN4 GFRA1
GH1 GH2 GLRX3 GLUL GMFB GMPS GNAI1
GNAI3 GNAO1 GNAT3 GNB1 GNB2 GNG2 GOPC
GPC4 GRAP2 GRB10 GRB2 GRIN2B GRWD1 GSK3B
GSN GSTM1 GSTM3 GSTP1 GTPBP4 GUK1 HADHA
HADHB HAND2 HBA1 HBG1 HCK HDAC2 HDAC5
HDAC6 HEATR5B HIRIP3 HIST1H1B HIST1H2BH HIST1H2BJ HIST1H3A
HIST1H3B HIST1H3C HIST1H3D HIST1H3E HIST1H3F HIST1H3G HIST1H3H
HIST1H3I HIST1H3J HIST1H4A HIST2H2AA3 HIST2H2AA4 HK2 HLA-DPA1
HLA-DPB1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DQB2 HLA-DRA HLA-DRB1
HLA-DRB3 HLA-DRB4 HLA-DRB5 HMGB1 HNRNPA1 HNRNPA2B1 HNRNPDL
HNRNPH2 HNRNPK HNRNPM HNRNPU HP1BP3 HRNR HSF1
HSP90AA1 HSP90AB1 HSPA1A HSPA1L HSPA5 HSPA6 HSPA8
HSPA9 HSPB1 HSPD1 HSPE1 HSPG2 HTRA1 HTT
HUNK ICAM1 ID2 IFNA1 IFNA10 IFNA14 IFNA16
IFNA17 IFNA2 IFNA21 IFNA4 IFNA5 IFNA6 IFNA7
IFNA8 IFNAR1 IFNAR2 IFNB1 IFNG IFNGR1 IFNGR2
IGF1R IGF2 IGHE IGHG1 IL1A IL2 IL2RA
IL2RB IL2RG IL3 IL3RA IL4 IL4R IL5
IL5RA IL6R IL6ST IL8 ILF2 ILF3 IMMT
IMPDH2 INCENP INPP5D INPPL1 INSR IPO5 IPO7
IQCB1 IQGAP1 IQGAP3 IRF3 IRF6 IRS1 IRS2
IRS4 ITGA11 ITGB3 ITK ITPR3 JAK1 JAK2
JAK3 JUN KAT5 KDR KIF24 KIR2DL1 KIR2DL2
KIR2DL3 KIR2DL4 KIR2DL5A KIR3DL1 KIR3DL2 KIT KITLG
KL KLB KLRC1 KLRD1 KLRG1 KPNA2 KPNB1
KRAS KRIT1 KRT1 KRT10 KRT17 KRT18 KRT33A
KRT36 KRT7 KRT8 KRT9 LAIR1 LARP1 LAT
LCK LDB1 LDHAL6A LDHB LEO1 LEP LEPR
LGALS1 LHX1 LIFR LILRA6 LILRB3 LILRB4 LIMA1
LMNA LMO2 LMO4 LMO7 LONP1 LOX LPA
LPCAT2 LRPPRC LRRFIP2 LRRK1 LTN1 LUC7L2 LUZP1
LY9 LYN LYPLA2 MACF1 MAG MAGED1 MALT1
MAP1B MAP3K5 MAPRE1 MATR3 MBD2 MCM2 MCM3
MCM4 MCM6 MDH1 MDH2 MEF2C MLLT4 MPL
MPP5 MPRIP MPZL1 MRPL16 MRPL43 MRPS23 MS4A2
MSI2 MSN MSR1 MTA2 MTPN MYC MYD88
MYH10 MYH14 MYH9 MYL12A MYL12B MYL4 MYL6
MYL9 MYO1A MYO1B MYO1C MYO3B MYO5B MYO6
N6AMT1 NAA15 NAP1L1 NAPA NAT10 NCKIPSD NDUFS1
NDUFS3 NEB NEFM NEXN NFATC1 NFATC2 NFATC3
NFATC4 NFKB1 NFKBIA NHP2L1 NONO NOS1 NOX1
NOX3 NOX4 NOX5 NPHS1 NPHS2 NPPB NR0B2
NRAS NRG1 NTF3 NTN1 NTRK1 NTRK3 NUDC
NUDT3 NUFIP1 NUP188 NUP205 NUP210 NXPE2 OGDH
OXCT1 PABPC1 PAF1 PAFAH1B1 PAFAH1B3 PAG1 PAICS
PANX1 PARD6A PARD6B PAWR PAX2 PCM1 PCMT1
PCP4 PCP4L1 PDCD1 PDCD10 PDCD6 PDGFA PDGFB
PDGFRA PDGFRB PDHA1 PDLIM7 PEA15 PEBP1 PECAM1
PEX11A PEX3 PFDN2 PFKL PGAM1 PGD PHB
PHGDH PI3 PI4K2A PI4KA PIK3CB PIK3CD PIK3CG
PIK3R2 PIK3R3 PIK3R5 PILRA PILRB PKM PLCB3
PLEC PLEKHA2 PLN PLS3 PNP PPIA PPIF
PPIH PPM1E PPP1CB PPP1CC PPP1R12A PPP1R9B PPP2CA
PPP2CB PPP2R1A PPP3CA PPP3R1 PPP6R3 PRDX3 PRELID1
PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKACA PRKACB PRKACG
PRKAG1 PRKAG2 PRKAR1A PRKAR1B PRKAR2A PRKAR2B PRKCA
PRKCB PRKCDBP PRKCH PRKCI PRKCZ PRKDC PRL
PRLR PRMT5 PRPS2 PRPSAP1 PRPSAP2 PSMA1 PSMA2
PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB2
PSMB3 PSMB5 PSMB6 PSMB7 PSMD11 PSMD2 PSMD3
PSME3 PSTPIP2 PTEN PTK2 PTK2B PTPN6 PTPRA
PTRF PVALB PXMP2 PYCR2 QARS QDPR RAB10
RAB14 RAB1A RAB35 RAB3A RAB3C RAB5A RAB5C
RAC1 RACGAP1 RAI14 RALY RAP1A RAP1B RAP2B
RAPGEF1 RBBP7 RBP4 RCC1 RCC2 RCN2 RELA
RET RFWD2 RGP1 RGS4 RGS6 RHOA RILP
RIPK1 RNH1 ROS1 RPIA RPL10 RPL10A RPL12
RPL13A RPL14 RPL18 RPL18A RPL21 RPL23 RPL23A
RPL24 RPL26 RPL27 RPL27A RPL28 RPL3 RPL30
RPL31 RPL35 RPL35A RPL36 RPL38 RPL4 RPL5
RPL7 RPL8 RPLP0 RPLP2 RPN1 RPS10 RPS11
RPS13 RPS14 RPS15A RPS16 RPS18 RPS19 RPS2
RPS20 RPS23 RPS24 RPS25 RPS26 RPS27A RPS28
RPS3 RPS3A RPS5 RPS6KB1 RPS7 RPS8 RPS9
RRBP1 RTF1 RUVBL1 RUVBL2 RYR2 S100A6 S100A8
SAFB2 SARS SCAP SCIN SCRIB SDC2 SEC16A
SEC31A SEC61B SELE SEMG1 SEMG2 SEPT11 SEPT7
SERPINH1 SET SF3B6 SGCG SGPL1 SH3BGRL2 SHB
SHC1 SHMT2 SIGLEC11 SIGLEC12 SIGLEC7 SIN3A SIRPA
SIT1 SKAP2 SKI SKIL SKP1 SLAMF1 SLAMF6
SLC22A6 SLC25A3 SLC25A4 SLC25A5 SLC27A5 SLC2A1 SLC4A1
SLC51B SLC5A3 SMAD2 SMAD6 SMAD7 SMARCA4 SMARCA5
SMC2 SMC3 SMC4 SMC5 SMC6 SMCHD1 SMN2
SMU1 SNAP29 SNRNP70 SNRPA1 SNRPD2 SNRPD3 SNX4
SOAT1 SOCS3 SOD1 SOX9 SPATA24 SPECC1 SPECC1L
SPP2 SPRY2 SPTAN1 SPTBN1 SPTBN5 SQRDL SRI
SRM SRP14 SRP9 SRSF10 SSBP1 SSBP3 SSRP1
SST SSTR1 SSX2IP STAP1 STAT1 STAT2 STAT5A
STIP1 STOM STON2 STRAP STX1A STXBP1 SUCLG1
SUCLG2 SVIL SVOPL SYNCRIP SYNPO SYP TAB1
TAL1 TALDO1 TAOK2 TARS TBK1 TEK TFAP2A
TFG TFRC THBS1 THOC2 THRAP3 TIA1 TIAF1
TIE1 TLE6 TLN1 TMEM102 TMOD3 TNF TNFRSF14
TNFRSF1A TOMM40L TOP1 TPI1 TPM1 TPM2 TPR
TRA@ TRAC TRADD TRAF6 TRAPPC3 TRB@ TRBC1
TRBV12-3 TREML1 TRIAP1 TRIM21 TRIM28 TRMT112 TRPC1
TRPC4 TTR TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E
TUBA4A TUBA4B TUBAL3 TUBB TUBB1 TUBB2A TUBB2B
TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 TUBE1 TUBG2
TUFM TWF2 TYK2 TYMS TYR UACA UBA52
UBASH3B UBB UBC UBE2D2 UBE2K UBE2N UBE2NL
UBE2V1 UBE3B UBL5 UBQLN1 UBR4 UCHL1 UGDH
UNC5C USP28 UVRAG VAMP2 VAPA VASP VAV1
VAV2 VAV3 VCL VCP VDAC1 VPS35 VPS72
WDR1 WDR61 WIPI2 XPO1 XPOT XRCC5 XRCC6
YBX1 YES1 YTHDF2 YWHAB YWHAG YWHAQ YWHAZ
ZAP70 ZFP42 ZNF703 ZYX
Data information
Please see the Gene Interactions Track Manual.