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ADA — CD4
Text-mined interactions from Literome
Blanco et al., FEBS Lett 2000
:
In cells lacking human CXCR4 expression, this gp120 mediated inhibition of
ADA binding to human CD26 was completely
dependent on the expression of human
CD4 ... These data suggest that the interaction of gp120 with
CD4 or CXCR4 is
required for efficient inhibition of
ADA binding to CD26, although in the presence of CXCR4 the interaction of gp120 with CD4 may be dispensable
Benveniste et al., Proc Natl Acad Sci U S A 1995
:
We demonstrate that
ADA deficiency
causes depletion of CD8low transitional and
CD4+CD8+ double positive thymocytes by an apoptotic mechanism