Gene interactions and pathways from curated databases and text-mining

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ADCYAP1 — TCF4

Text-mined interactions from Literome

Wong et al., Ann N Y Acad Sci 2002 : Although PACAP stimulates rapid changes in transcription factor expression and PNMT promoter activity, its effects are long lasting
Farini et al., Endocrinology 2003 (Prostatic Neoplasms) : Moreover, PACAP stimulates phosphory-lation and activation of the cAMP response element binding transcription factor ( CREB ), and MAPK activation is necessary for its full transcriptional activity, indicating a direct involvement of cAMP response element in PACAP action
von Gall et al., Neurobiol Aging 2008 : One of the most robust assays for SCN melatonin receptor activation in mice is the inhibition of PACAP induced phosphorylation of the transcription factor Ca ( 2+ ) /cAMP responsive element binding protein ( CREB )