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AHR — SELL
Text-mined interactions from Literome
Funatake et al., J Immunotoxicol 2008
(Graft vs Host Disease) :
When CD4+ and CD8+ donor T-cells from AhR-WT and AhR-KO mice were injected in various combinations into F1 mice, the enhanced expression of CD25 on CD8+ T-cells required AhR in donor CD4+ T-cells, while down-regulation of
CD62L required
AhR in the donor CD8+ T-cells themselves
Funatake et al., J Immunotoxicol 2009
(Disease Models, Animal...) :
Expression of constitutively-active
aryl hydrocarbon receptor in T-cells
enhances the down-regulation of
CD62L , but does not alter expression of CD25 or suppress the allogeneic CTL response ... Expression of
CA-AhR in donor T-cells
enhanced the down-regulation of
CD62L on Day 2 after injection, similar to a single oral dose of TCDD, but did not induce up-regulation of CD25 on Day 2 or affect CTL activity on Day 10