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AICDA — CD40

Text-mined interactions from Literome

Zan et al., Immunity 2003 : Upon CD40 induced expression of activation induced cytidine deaminase ( AID ), DSBs increase in frequency and are resected to yield 5'- and 3'-protruding ends in hypermutating rearranged V genes, BCL6 and translocated c-MYC
Dedeoglu et al., Int Immunol 2004 : Induction of activation induced cytidine deaminase gene expression by IL-4 and CD40 ligation is dependent on STAT6 and NFkappaB
Klapper et al., J Pathol 2006 (Lymphoma, Mantle-Cell) : Similar to the situation in normal B cells, in vitro stimulation of MCL cell lines with CD40 ligand (CD40L) and interleukin-4 induced expression of activation induced cytidine deaminase ( AID ) and germline transcription at the immunoglobulin heavy chain gene locus