◀ Back to NOTCH3

APEH — NOTCH3

Text-mined interactions from Literome

Francis et al., Dev Cell 2002 (Alzheimer Disease) : aph-1 and pen-2 are required for Notch pathway signaling, gamma-secretase cleavage of betaAPP, and presenilin protein accumulation
Lee et al., J Biol Chem 2004 : The multipass membrane protein APH-1 , found in the gamma-secretase complex together with presenilin, nicastrin, and PEN-2, is essential for Notch signaling in Caenorhabditis elegans embryos and is required for intramembrane proteolysis of Notch and beta-amyloid precursor protein in mammalian and Drosophila cells