Gene interactions and pathways from curated databases and text-mining

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ARG2 — NFKB1

Text-mined interactions from Literome

Klasen et al., Br J Pharmacol 2001 : 5. Two different inhibitors of the NF-kappa B-pathway also prevented LPS induced increase in arginase activity
Rakonczay et al., Free Radic Biol Med 2003 (Acute Disease...) : We demonstrated that Arg specifically and dose-dependently induces pancreatitis, activates NF-kappaB ( only the 3 g/kg dose ) and proinflammatory cytokine synthesis, and increases the expressions of HSP60 and HSP72 in the pancreas of rats
Yang et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2003 : L-Arg augmented CSE induced NF-kappaB activation and decreased I-kappaB content at low concentration while inhibited CSE induced NF-kappaB activation at high concentration, but there was not any significant difference of the expression of I-kappaB
Moreau et al., Mol Pharmacol 2007 : Lys-des-Arg9-bradykinin had little effect on NF-kappaB activation, the Bmax, or receptor mRNA abundance or stability
Ckless et al., Am J Respir Cell Mol Biol 2007 : Our results demonstrate that reduction of arginase activity enhanced cellular content of NO and S-nitrosated proteins, and resulted in decreases in TNF-alpha- or LPS stimulated NF-kappaB DNA binding and transcriptional activity, in association with enhanced S-nitrosation of p50