Gene interactions and pathways from curated databases and text-mining

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ASS1 — IL1B

Text-mined interactions from Literome

Brasse-Lagnel et al., Biochimie 2006 : Biphasic effect of IL-1beta on the activity of argininosuccinate synthetase in Caco-2 cells ... Conversely, blocking the action of NO by antioxidant agents, the stimulatory effect of IL-1beta on ASS activity was restored, as measured at 24 h
Brasse-Lagnel et al., FEBS J 2007 : We previously demonstrated that the expression of the argininosuccinate synthetase (ASS) gene, a key step in nitric oxide production, is stimulated either by interleukin-1beta [ Brasse-Lagnel et al. ( 2005 ) Biochimie 87, 403-9 ] or by glutamine in Caco-2 cells [ Brasse-Lagnel et al. ( 2003 ) J. Biol. Chem. 278, 52504-10 ], through the activation of transcription factors nuclear factor-kappaB and Sp1, respectively