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ATF2 — IL1B
Text-mined interactions from Literome
Clerk et al., J Mol Cell Cardiol 1999
(MAP Kinase Signaling System) :
IL-1 beta and TNF alpha
stimulated the phosphorylation of c-Jun and
ATF2
Robbins et al., Arthritis Rheum 2000
:
IL-1beta also
stimulated phosphorylation of p38 MAPK, SAPK/JNK, and
ATF-2
Sooranna et al., J Cell Physiol 2007
(MAP Kinase Signaling System) :
All three stimuli increased PGHS-2 and IL-8 mRNA expression in a MAPK dependent manner, but while the MAPK inhibitors reduced the
IL-1beta induced activation of activating transcription factor
(ATF)-2 , liver activating protein (LAP) and c-jun, the stretch induced increase in LAP was unaffected by MAPK-inhibition and only JNK inhibition appeared to reduce c-jun activation
Tseng et al., Biochem Pharmacol 2008
:
HE-145 specifically suppressed IL-1beta induced c-jun mRNA and protein expression and prevented c-jun mediated AP-1 DNA binding activity, whereas it had no effect on
IL-1beta induced
activation of JNK, p38 and
ATF2