Gene interactions and pathways from curated databases and text-mining

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BCAP31 — CASP4

Text-mined interactions from Literome

Chandra et al., Mol Cell Biol 2004 : Finally, we present evidence that the OMM localized active caspase 8 can activate cytosolic caspase 3 and ER-localized BAP31
Panaretakis et al., EMBO J 2009 : Early activation of the endoplasmic reticulum ( ER ) -sessile kinase PERK leads to phosphorylation of the translation initiation factor eIF2alpha, followed by partial activation of caspase-8 ( but not caspase-3 ), caspase-8 mediated cleavage of the ER protein BAP31 and conformational activation of Bax and Bak