UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to MCL1

BCL2A1 — MCL1

Pathways - manually collected, often from reviews:

NCI Pathway Database Direct p53 effectors: BCL2 subfamily (BCL2/MCL1/BCL2L2/BCL2A1/BCL2L1) → p53/BCL2 subfamily complex (TP53-BCL2_MCL1_BCL2L2_BCL2A1_BCL2L1) (modification, collaborate)
Mihara et al., Mol Cell 2003, Marchenko et al., EMBO J 2007
Evidence: physical interaction
NCI Pathway Database Direct p53 effectors: PUMA/BCL2 subfamily complex (BBC3-BCL2_MCL1_BCL2L2_BCL2A1_BCL2L1) → p53/BCL2 subfamily complex (TP53-BCL2_MCL1_BCL2L2_BCL2A1_BCL2L1) (modification, collaborate)
Chipuk et al., Science 2005
Evidence: mutant phenotype, physical interaction, other species