Gene interactions and pathways from curated databases and text-mining

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BMP7 — GNRH1

Text-mined interactions from Literome

Otani et al., J Endocrinol 2009 : Treatment with BMP2 and BMP4 had no effect on Gnrh mRNA expression ; however, BMP6 and BMP7 significantly increased Gnrh mRNA expression as well as GnRH production by GT1-7 cells ... Treatment with BMP2 and BMP4 had no effect on Gnrh mRNA expression ; however, BMP6 and BMP7 significantly increased Gnrh mRNA expression as well as GnRH production by GT1-7 cells ... Considering that BMP6 and BMP7 increased the expression of alpha1E-subunit of R-type calcium channel ( Cacna1e ), which is critical for GNRH secretion, it is possible that BMP6 and BMP7 directly stimulate GNRH release by GT1-7 cells
Takeda et al., Mol Cell Endocrinol 2012 (MAP Kinase Signaling System) : Here, we describe a functional link between BMP-6 and BMP-7 signals and FSH transcriptional activity induced by GnRH using mouse gonadotrope LßT2 cells