Gene interactions and pathways from curated databases and text-mining

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BMX — STAT3

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Tsai et al., Mol Cell Biol 2000 (Cell Transformation, Neoplastic) : Furthermore, Etk activated STAT3 mediated gene expression in synergy with this Src mutant
Jui et al., J Biol Chem 2000 : The Etk-PTPD1 interaction also increased Stat3 activation
Willey et al., International journal of biological sciences 2008 (Hypertrophy) : STAT3 activation in pressure overloaded feline myocardium : role for integrins and the tyrosine kinase BMX ... Therefore, these studies indicate a novel mechanism of BMX mediated STAT3 activation within a PO model of cardiac hypertrophy that might contribute to cardiomyocyte growth and survival
Guryanova et al., Cancer Cell 2011 (Brain Neoplasms...) : Here we demonstrate that the bone marrow X-linked (BMX) nonreceptor tyrosine kinase activates STAT3 signaling to maintain self-renewal and tumorigenic potential of GSCs. BMX is differentially expressed in GSCs relative to nonstem cancer cells and neural progenitors
Vogt et al., Cancer Discov 2011 (Neoplasms) : Phosphorylation of STAT3 in PI3K transformed murine cells is mediated by the TEC kinase BMX