Gene interactions and pathways from curated databases and text-mining

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Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Edlich et al., J Biol Chem 2007 : The direct interaction between FKBP38 and Bcl-2 , however, requires a prior activation of FKBP38 by the Ca2+ sensor calmodulin (CaM)
Botez et al., Neuropathol Appl Neurobiol 2001 (Brain Ischemia) : We conclude that : ( 1 ) the presence of C-Jun and Bcl-2 within the glucose polymer mass of CAm may be related to mitochondrial damage and/or a transient overload of proteolytic systems during cellular injury ; and ( 2 ) repetitive cellular stress during life may cause the age related increase of CAm in elderly subjects
Erin et al., Neuroscience 2003 (Hypoxia-Ischemia, Brain) : Experiments involving cell-free systems, as well as brain slices treated with thapsigargin or with N-methyl-D-aspartate suggested that calcium and calmodulin activation of calcineurin leads to interactions between calcineurin and Bcl-2
Edlich et al., EMBO J 2005 : Bcl-2 regulator FKBP38 is activated by Ca2+/calmodulin