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CAMK1 — CYP1A1
Text-mined interactions from Literome
Monteiro et al., Mol Pharmacol 2008
(Breast Neoplasms) :
Small interfering RNA ( siRNA ) -mediated knockdown expression of
CaMKIalpha , one of the CaMK isoforms, similarly
prevented CYP1A1 up-regulation
Monteiro et al., Drug Metab Dispos 2008
(Calcium Signaling) :
As already reported for AhR agonists, STO-609 triggered the increase of [ Ca2+ ] ( i ) and activation of
CaMKIalpha , whose inhibition through the use of the Ca2+ chelator 1,2-bis ( 2-aminophenoxy ) ethane-N, N,N ', N'-tetraacetic acid-acetoxymethyl ester or the CaMK inhibitor KN-93 ( 2- [ N- ( 2-hydroxyethyl ) ] -N- ( 4-methoxybenzenesulfonyl ) ] amino-N- ( 4-chlorocinnamyl ) -N-methylbenzylamine ), respectively,
prevented STO-609 mediated
CYP1A1 activity induction