Gene interactions and pathways from curated databases and text-mining

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CAPN11 — TNF

Text-mined interactions from Literome

Wang et al., J Hepatol 2001 (Reperfusion Injury) : Cytoprotective effect of prednisolone in hepatic IR injury was closely associated with suppression of IL-beta/TNF-alpha production and calpain mu activation
Zhao et al., J Neurosci Res 2001 : Results of this study suggest TNF-alpha may induce caspase-3 activation but not calpain activation in septo-hippocampal cultures and that this activation of caspase-3 at least partially contributes to TNF-alpha induced apoptosis
Coward et al., Clin Exp Allergy 2004 : The NF-kappaB inhibitors, calpain inhibitor 1 ( 10 microm ), pentoxifylline ( 0.5 mm ), pyrrolidine dithiocarbamate ( PDTC, 10 microm ) or gliotoxin ( 1 pg/mL ) reduced the generation of GM-CSF, TNF-alpha and IL-8 in parallel with their inhibition of NF-kappaB
Morita et al., Biochem Biophys Res Commun 2006 (Arthritis, Rheumatoid) : Tumor necrosis factor ( TNF-alpha ) stimulation induced increased expression of mu-calpain, m-calpain , and MMP-3 in these cells, as well as the release of calpain and MMP-3 into the culture medium
Li et al., Cardiovasc Res 2009 (Disease Models, Animal...) : gp91(phox)-NADPH oxidase mediated calpain-1 activation induces caspase-3 activation and TNF-alpha expression in cardiomyocytes during LPS stimulation