Gene interactions and pathways from curated databases and text-mining

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BRCA1 — CASP6

Text-mined interactions from Literome

Zhan et al., Oncogene 2002 : Altogether, results of our study demonstrate a functional role for caspase-3 mediated cleavage of BRCA1 during UV-induced apoptosis
Broustas et al., J Biol Chem 2004 (Prostatic Neoplasms) : BRCC2 , a novel BH3-like domain containing protein, induces apoptosis in a caspase dependent manner
Martin et al., Cancer Res 2005 : BRCA1 phosphorylation regulates caspase-3 activation in UV-induced apoptosis
Dizin et al., Apoptosis 2008 (Breast Neoplasms) : We showed that chemotherapy induced apoptosis leads to a caspase mediated cleavage of BRCA1