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CASP7 — HMOX1

Text-mined interactions from Literome

Lang et al., Int Immunol 2005 : We studied the effects of heme oxygenase-1 (HO-1) induced by its substrate hemin on apoptosis, caspase-3 expression and the differentiation of freshly isolated human monocytes
Conde de la Rosa et al., Free Radic Biol Med 2008 (Liver Diseases...) : The results showed that ( 1 ) HO-1 is induced in chronic cholestatic liver disease, ( 2 ) superoxide anions time- and dose-dependently induce HO-1 activity, ( 3 ) HO-1 overexpression inhibits superoxide-anions induced apoptosis, and ( 4 ) CO blocks superoxide-anions induced JNK phosphorylation and caspase-9 , -6, -3 activation and abolishes apoptosis but does not increase necrosis
Kim et al., Autophagy 2008 (Necrosis...) : Adenoviral mediated expression of HO-1 inhibited DISC formation and caspase-3/9 activation in CSE treated epithelial cells, diminished the expression of Beclin 1, and partially inhibited the processing of LC3B-I to LC3B-II
Hao et al., Free Radic Biol Med 2013 : The blockade of VEGFR-2 function also elicited a cytotoxicity that was accompanied by caspase-3 activation, induction of hemeoxygenase-1 (HO-1) , oxidative stress, and a collapse in the mitochondrial membrane potential ( d?m )