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CCL2 — SMN1

Text-mined interactions from Literome

Kruglov et al., Am J Physiol Gastrointest Liver Physiol 2006 : MCP-1 induces proliferation, increase and redistribution of alpha-smooth muscle ( alpha-SMA ) expression, loss of the ectonucleotidase NTPDase2, and upregulation of alpha ( 1 ) -procollagen production in PF. BDE secretions induce alpha-SMA levels in PF, and this is inhibited by MCP-1 blocking antibody
Carulli et al., Arthritis Rheum 2005 (Scleroderma, Systemic) : In these cultures, specific inhibition of CCL2 or CCR2 attenuated the overexpression of alpha-SMA , but not CTGF or plasminogen activator inhibitor 1
Locatelli et al., J Biol Chem 2012 : a-SMN dependent induction of CCL2 and IGF1 mRNAs resulted in increased intracellular levels and secretion of the respective protein products