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CCND2 — CD79B
Text-mined interactions from Literome
Banerji et al., Oncogene 2001
(Lymphoma, B-Cell...) :
We show that
BCR stimulation of WEHI 231 cells
results in down-regulation of
cyclin D2 and up-regulation of p27 ( Kip1 ), which are associated with pocket protein hypophosphorylation and E2F inactivation
Piatelli et al., J Biol Chem 2002
:
Disruption of endogenous heat shock protein 90 (hsp90) function with geldanamycin abrogated
BCR induced
cyclin D2 expression and proliferation
Glassford et al., Oncogene 2003
(Calcium Signaling...) :
Collectively, these data provide evidence for the concept that the B-cell signalosome ( p85alpha, Btk, BLNK and PLCgamma ) is involved in regulating
cyclin D2 expression in
response to
BCR engagement
Glassford et al., Eur J Immunol 2005
:
Furthermore, using both p85alpha-null and p110delta-null B cells and inhibitors of PI3K, this study demonstrates for the first time, that
BCR cross linking induces cyclin D2 mRNA expression via transcriptional activation of the cyclin D2 promoter and that this transcriptional activation of
cyclin D2 requires PI3K activity
Xing et al., J Exp Med 2005
:
G5pr(-/-) B cells did not show abnormalities in the
BCR mediated activation of Erks and NF-kappaB,
cyclin D2 induction, or Akt activation