Gene interactions and pathways from curated databases and text-mining

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CD40 — IL32

Text-mined interactions from Literome

Bartholomé et al., J Interferon Cytokine Res 1999 : IFN-beta interferes with the differentiation of dendritic cells from peripheral blood mononuclear cells : selective inhibition of CD40 dependent interleukin-12 secretion
Kitagawa et al., Arthritis Rheum 1999 (Arthritis, Rheumatoid) : Differential regulation of rheumatoid synovial cell interleukin-12 production by tumor necrosis factor alpha and CD40 signals
Muraille et al., Blood 1999 : Anti-CD3epsilon treatment was found to induce a selective deficiency in the ability of spleen cells to produce bioactive interleukin-12 in response to CD40 stimulation
Cattaruzza et al., J Biol Chem 2003 : Interleukin-10 induction of nitric-oxide synthase expression attenuates CD40 mediated interleukin-12 synthesis in human endothelial cells
Pinzon-Charry et al., Neoplasia (New York, N.Y.) 2005 (Adenocarcinoma...) : Importantly, despite DR ( + ) IC 's poor responsiveness to inflammatory factors, in samples from healthy volunteers and breast cancer patients, CD40 ligation induced phenotypic maturation and interleukin 12 secretion, in turn generating more efficient T-cell responses
Danese et al., Gut 2007 (Colitis...) : Engagement of CD40 on HIFs promoted the release of vascular endothelial growth factor ( VEGF ), interleukin-8 (IL-8) and hepatocyte growth factor (HGF)
Bose et al., Hum Immunol 2007 (Carcinoma, Squamous Cell...) : Natural killer cell mediated cytotoxicity of tumor cells initiated by neem leaf preparation is associated with CD40-CD40L mediated endogenous production of interleukin-12
Kennedy et al., Eur J Immunol 1996 : CD40/CD40 ligand interactions are required for T cell dependent production of interleukin-12 by mouse macrophages
Cella et al., J Exp Med 1996 : Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity : T-T help via APC activation
Yoshimoto et al., Eur J Immunol 1997 : Induction of interleukin-12 p40 transcript by CD40 ligation via activation of nuclear factor-kappaB
Séguin et al., J Infect Dis 1999 : Sensitized lymphocytes and CD40 ligation augment interleukin-12 production by human dendritic cells in response to Toxoplasma gondii