Gene interactions and pathways from curated databases and text-mining

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CD40LG — IRF6

Text-mined interactions from Literome

Mehlhop et al., J Immunol Methods 2002 (Simian Acquired Immunodeficiency Syndrome) : In general, macaque DCs exhibited weaker responses to LPS and Poly I:C than human DCs, and soluble CD40L stimulation induced variable expression of CD25
Andreakos et al., Blood 2003 : In summary, our results demonstrate that IKK2 is essential for DC activation induced by CD40L or contact with allogeneic T cells, but not by LPS , whereas NIK is not required for any of these signals
Arrighi et al., Eur J Immunol 2003 : When added to GM-CSF, IL-4 and TGF-beta1 containing-cultures, LPS or IL-1beta also induced significant numbers of Langerin+CD83- immature cells displaying a low allostimulatory activity, while CD40-ligand largely promoted highly allostimulatory Langerin-CD83+ cells
Geyeregger et al., Blood 2007 : Immunologic synapse formation was significantly inhibited by LXR activation along with a complete block in LPS- but not CD40L induced expression of the actin bundling protein fascin
Alabraba et al., Hepatology 2008 (Liver Diseases) : We report that lipopolysaccharide (LPS) and interferon ( IFN ) induce sustained expression of CD154 on liver derived macrophages (LDM) in vitro
Ma et al., Zhongguo Shi Yan Xue Ye Xue Za Zhi 2009 : It may involve in platelet activation as an important mediator of LPS induced CD62P and CD40L expressions on platelets
Dohnal et al., J Cell Mol Med 2009 : Accordingly, we demonstrated that CD40/CD40L but not TLR4 or TLR3 signalling mediated by LPS or poly ( cytidylic-inosinic ) acid ( poly I:C ) and dsRNA re-established the capacity for secreting interleukin (IL)-12 in primarily LPS/IFN-gamma activated DCs, which have exhausted their potential for cytokine secretion
Jang et al., Arch Oral Biol 2011 (Inflammation...) : The n-butanol extracts of PN ( bPN ) increased the cell proliferation of the PDLFs and decreased the mRNA expression of matrix metalloproteinase (MMP)-2 in the PDLFs. bPN inhibited the formation of LPS stimulated TRAP ( + ) multinucleated cells
Park et al., PloS one 2011 : Capric acid reduced LPS induced TRAP expression, an osteoclast differentiation marker, without inhibiting cell viability