UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

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CDC37 — CDK5

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

IRef Biogrid Interaction: CDC37 — CDK5 (direct interaction, two hybrid) Soler-López et al., Genome Res 2011
IRef Biogrid Interaction: CDC37 — CDK5 (physical association, affinity chromatography technology) Varjosalo et al., Nat Methods 2013
IRef Intact Interaction: CDK5 — CDC37 (physical association, two hybrid array) Soler-López et al., Genome Res 2011

Text-mined interactions from Literome

Jallepalli et al., Genes Dev 1996 : Rum1 and Cdc18 link inhibition of cyclin dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe
Kimura et al., Genes Dev 1997 : Cdc37 is required for cyclin dependent kinase activation and is genetically linked with the activity of several other kinases, including oncogenic v-Src, casein kinase II, MPS-1 kinase, and sevenless