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CDC42 — TERF2

Text-mined interactions from Literome

Fukuyama et al., J Biol Chem 2005 : Involvement of the c-Src-Crk-C3G-Rap1 signaling in the nectin induced activation of Cdc42 and formation of adherens junctions ... These results indicate that Rap1 is activated by nectins through the c-Src-Crk-C3G signaling and involved in the nectin induced, c-Src- and FRG mediated activation of Cdc42 and formation of AJs
Sato et al., Cancer Sci 2005 : The activation of Cdc42 and Rac by the trans-interaction of nectin and nectin is mediated by c-Src, another small G protein, Rap1 , a Cdc42-GEF, FRG, and a Rac-GEF, Vav2 ... The trans-interaction of Necl-5 and nectin-3 also activates Rap1 through C3G, a Rap-GEF, and this activation of Rap1 is required for the activation of Cdc42 and Rac
Gérard et al., J Cell Biol 2007 : Intracellular localization and activation of the Par complex are initiated by Rap1 and require Cdc42 activity
Kempf et al., Nat Med 2011 (Myocardial Infarction) : Mechanistically, GDF-15 counteracted chemokine triggered conformational activation and clustering of ß ( 2 ) integrins on PMNs by activating the small GTPase Cdc42 and inhibiting activation of the small GTPase Rap1