Debiais et al., J Cell Biochem 2001
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We investigated the effects of FGF-2 on cell-cell adhesion and cadherin expression and the underlying signaling pathways in immortalized human neonatal calvaria ( IHNC ) cells
Ciruna et al., Dev Cell 2001
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We propose that modulation of cytoplasmic beta-catenin levels, associated with FGF induced downregulation of E-cadherin , provides a molecular link between FGF and Wnt signaling pathways at the streak
Wu et al., Exp Cell Res 2008
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But the mRNA or total protein of cadherins had no significant change, suggesting that the effect of bFGF on cadherin expression may work through a post-translational control
Hatanaka et al., PloS one 2012
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In vitro studies demonstrated that the loss of FGF signaling disrupts the VE-cadherin-catenin complex at adherens junctions by increasing tyrosine phosphorylation levels of VE-cadherin