Gene interactions and pathways from curated databases and text-mining

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CDH5 — XRCC5

Text-mined interactions from Literome

Sakurai et al., Mol Biol Cell 2006 : We demonstrate for the first time that Rap1 is activated upon homophilic engagement of vascular endothelial cadherin ( VE-cadherin ) at the cell-cell contacts in living cells and that MAGI-1 is required for VE-cadherin dependent Rap1 activation ... Collectively, MAGI-1 is important for VE-cadherin dependent Rap1 activation upon cell-cell contact
Retta et al., Eur J Cell Biol 2006 : This review focuses on recent findings on the involvement of the small GTPase Rap1 in the regulation of cadherin- and integrin dependent cell adhesion and signal transduction
Kanemura et al., Biochem Biophys Res Commun 2009 : Reduced accumulation of VE-cadherin at cell-cell junctions and defects in blood vessel formation in vitro due to the lack of RA-GEF-1 were suppressed by ectopic expression of constitutively activated Rap1