Gene interactions and pathways from curated databases and text-mining

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CHKA — XRCC5

Text-mined interactions from Literome

Li et al., J Biol Chem 2005 : Down-regulation of DNA-PK ( cs ) by either siRNA or a chemical inhibitor attenuated radiation induced Chk2 phosphorylation
Rodríguez-Bravo et al., Cancer Res 2006 : Neither wortmannin, Ly294002, nor SB202190 abrogated the caffeine-insensitive checkpoint response, indicating that DNA-PK and p38 alpha, beta are not involved in the ATR/ATM independent Chk1 activation upon DNA synthesis inhibition
Solier et al., Mol Cell Biol 2009 : H2AX phosphorylation was dependent on DNA-PK, while Chk2 phosphorylation was dependent on both ATM and DNA-PK