Miyamori et al., J Biol Chem 2001
:
These results suggest that claudin recruits all MT-MMPs and pro-MMP-2 on the cell surface to achieve elevated focal concentrations and, consequently, enhances activation of pro-MMP-2 Lee et al., Histol Histopathol 2008
(Adenocarcinoma...) :
Claudin-4 has been shown to activate MMP-2 , indicating that claudin mediated increased cancer cell invasion might be mediated through the activation of MMP proteins