Gene interactions and pathways from curated databases and text-mining

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CNR2 — IL6

Text-mined interactions from Literome

Merighi et al., Br J Pharmacol 2012 (Inflammation) : We examined the effects of µ-opioid and CB(2) receptor stimulation on phosphorylation of MAPKs and Akt and on IL-1ß, TNF-a, IL-6 and NO production in primary mouse microglial cells
Bouchard et al., J Neurosci 2012 (Disease Models, Animal...) : CB(2) receptors regulate blood interleukin-6 (IL-6) levels, and IL-6 neutralizing antibodies partially rescue motor deficits and weight loss in HD mice