◀ Back to TGFB1

COL1A1 — TGFB1

Text-mined interactions from Literome

Williams et al., Tissue Eng 2003 : Type I collagen gene expression decreased from 3 to 6 weeks in the presence of TGF-beta1
Ortega-Velazquez et al., Am J Physiol Cell Physiol 2004 : Collagen I upregulates extracellular matrix gene expression and secretion of TGF-beta 1 by cultured human mesangial cells
Cutroneo et al., J Cell Biochem 2006 : Both Bleomycin and TGF-beta1 increase the transcription of the COL1A1 gene
Li et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2007 : Collagen I and HSP47 expression could be induced by both 1 ng/mL and 10 ng/mL TGF-beta(1) and collagen I was expressed the most after the treatment with 10 ng/mL TGF-beta(1)
Fu et al., J Orthop Res 2008 (Tendon Injuries) : TGF-beta1 increased COL1A1 and decorin mRNA in CTFs, but decreased the mRNA of all four genes in day 7 healing tendon fibroblasts
Hu et al., Zhong Nan Da Xue Xue Bao Yi Xue Ban 2007 : TGF-beta1 could induce the transcription and secretion of Type I collagen in HLF-02 cells ( P < 0.05 ) ... AP-1 is responsible for the secrection of TGF-beta1 induced Type I collagen in human lung fibroblasts
Chan et al., Wound Repair Regen 2008 (Disease Models, Animal...) : In cultured tendon fibroblasts, we tested the effects of TGF-beta1 , beta2, and beta3 on the mRNA levels of COL1A1 and COL3A1 by quantitative real-time polymerase chain reaction
Guo et al., Am J Physiol Lung Cell Mol Physiol 2009 : Treatment of normal human lung fibroblasts ( NHLFs ) with the pan-HDAC inhibitor trichostatin A (TSA) inhibited TGF-beta1 mediated alpha-smooth muscle actin ( alpha-SMA ) and alpha1 type I collagen mRNA induction
Tan et al., Respir Res 2010 : Since PPAR gamma ligands have been shown to inhibit fibroblast activation by TGF-beta1, we assessed the ability of the thiazolidinediones rosiglitazone ( RGZ ) and ciglitazone ( CGZ ) to regulate TGF-beta1 mediated EMT of A549 cells, assessing changes in cell morphology, and expression of cell adhesion molecules E-cadherin ( epithelial cell marker ) and N-cadherin ( mesenchymal cell marker ), and collagen 1 alpha 1 (COL1A1) , CTGF and MMP-2 mRNA ... However, both RGZ and CGZ inhibited the marked elevation of N-cadherin and COL1A1 induced by TGF-beta1 ( 2.5 ng/ml ), with effects on COL1A1 prevented by GW9662