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CR2 — TCF4

Text-mined interactions from Literome

D'Addario et al., J Mol Biol 2001 : To our knowledge this is the first report showing that the binding of a herpesvirus envelope glycoprotein to CR2 on human B cells results in the activation of the NF-kappaB transcription factor leading to the upregulation of IL-6 gene expression in these lymphocytes
Sugano et al., J Exp Med 1997 : Studies of the mechanisms that enable EBV to infect nonactivated, noncycling B cells provide compelling evidence for a sequence of events in which EBV binding to CD21 on purified resting human B cells rapidly activates the NF-kappaB transcription factor , which, in turn, binds to and mediates transcriptional activation of Wp, the initial viral latent gene promoter