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CA2 — CSF2
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Köller et al., AIDS 2001
(AIDS Dementia Complex) :
To investigate the
effect of
cerebrospinal fluid (CSF) of HIV-1-seropositive patients with and without HIV-1 associated dementia complex ( HADC ) on the intracellular
Ca2+ regulation of cultured cortical astrocytes
Baxter et al., Biochemistry 1992
:
Consistent with the involvement of PKC epsilon,
GM-CSF appears to activate phospholipase D and does not
cause a detectable increase in cytosolic
[Ca2+ ]
Fujisaki et al., Life Sci 2007
:
These results indicate that the expression of
CAII , cathepsin K, and MMP-9 in RAW264.7 cells is not
induced by
M-CSF , but by RANKL in the presence of IL-1alpha
Yuo et al., Blood 1989
:
rhG-CSF neither
affected stimulus induced increase in cytoplasmic free
Ca2+ nor changed the number and affinity of N-formyl-methionyl-leucyl-phenylalanine receptors
Kelso et al., Growth Factors 1989
:
The data suggest that
Ca2 ( + ) -independent ( CsA-resistant ) T cell activation
induces synthesis of
GM-CSF and IFN-gamma but is a poor stimulus for IL-3 production
Miller et al., J Clin Invest 1988
:
Additional stimulation with
GM-CSF in cells previously exposed to erythropoietin
resulted in a second [
Cac ] increase
Weyne et al., Pflugers Arch 1983
:
In anaesthetized normocapnic dogs
CSF [ HCO-3 ] was increased to ca 33 mmol/l by perfusing the brain ventricles for 45 min with a mock CSF containing a high [ HCO-3 ] which in addition contained 2.5 mg/ml acetazolamide to
inhibit central
carbonic anhydrase
Morin et al., EMBO J 1994
:
We ruled out this possibility by showing that competitive inhibition of the ubiquitin dependent degradation pathway still prevents the onset of anaphase in cycling extracts that lack
CSF and do not
require Ca2+ for sister chromatid separation
Zhang et al., Zygote 1996
:
In the present study, we report that 2 degrees
CSF activity can be induced in cytosols extracted from stage VI oocytes, unfertilised eggs, electrically activated eggs or blastulae, in the
presence of
Ca2+
Denecker et al., Cytokine 1997
:
TNF induced apoptosis still occurred in the absence of free Ca2+, while
GM-CSF production
required the continuous presence of
Ca2+