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Nishioka et al., Eur J Immunol 2003
(MAP Kinase Signaling System) :
Here, we show that HP-NAP induces extracellular regulated kinase (ERK) and p38-mitogen activated protein kinase ( MAPK ) activation in human neutrophils ; c-Jun N-terminal kinase is not activated by HP-NAP ... These results demonstrate that HP-NAP activates neutrophils through a PTX-sensitive pathway and that ERK and p38-MAPK are involved in many neutrophil functions stimulated by HP-NAP
Belugali Nataraj et al., Cell Signal 2013
(Breast Neoplasms...) :
NAP is phosphorylated by VEGF induced activation of MAPK and JNK pathways through VEGFR2 phosphorylation
Di Battista et al., Arthritis Rheum 1999
(Osteoarthritis) :
NIM, but not NAP , markedly increased MAPK phosphorylation ( suggesting an increase in MAPK cascade activity ), GR phosphorylation, GR binding to GRE, and transcriptional activation of MMTV promoter through the GRE site in the promoter