Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Bird et al., Biochem Biophys Res Commun 1992 : The effects of novel cathepsin E inhibitors on the big endothelin pressor response in conscious rats
Andoh et al., Eur J Pharmacol 2012 (Pruritus) : Cathepsin E induces itch related response through the production of endothelin-1 in mice ... These results suggest that cathepsin E is an endogenous itch inducer, and that its action is mediated at least in part by the production of endothelin-1 in the epidermis