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CAPN2 — CXCR3
Text-mined interactions from Literome
Bodnar et al., J Cell Sci 2009
:
We found that activation of
CXCR3 triggers
micro-calpain activity, causing cleavage of the cytoplasmic tail of beta3 integrins at the calpain cleavage sites c'754 and c'747
Yates-Binder et al., PloS one 2012
:
Inhibition of endothelial function by IP-10p was similar to that described for IP-10, secondary to
CXCR3 mediated increase in cAMP production, activation of PKA inhibiting cell migration, and inhibition of VEGF mediated
m-calpain activation