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DEFB103B — TLR2
Text-mined interactions from Literome
Funderburg et al., Proc Natl Acad Sci U S A 2007
:
Here, we show that
human beta-defensin-3 (hBD-3) , an innate antimicrobial peptide, can induce expression of the costimulatory molecules CD80, CD86, and CD40, on monocytes and myeloid dendritic cells in a
TLR dependent manner
Büchau et al., J Invest Dermatol 2008
:
We observed that pimecrolimus enhances distinct expression of cathelicidin, CD14, and human beta-defensin-2 and
beta-defensin-3 in
response to
TLR2/6 ligands
Scharf et al., Respir Res 2010
:
Inhibition of TLR2,
TLR5 , and TLR9 expression
led to a decreased
hBD-3 expression
Paoletti et al., Arch Dermatol Res 2012
(MAP Kinase Signaling System) :
In addition, the HBD-2 and
HBD-3 AV119 induced gene expression and release are
TLR-2 dependent