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ATF4 — DISC1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind_translation Interaction: ATF4 — DISC1 (two hybrid) Millar et al., Biochem Biophys Res Commun 2003
• IRef Bind_translation Interaction: ATF4 — DISC1 (two hybrid) Morris et al., Hum Mol Genet 2003
• IRef Biogrid Interaction: ATF4 — DISC1 (direct interaction, two hybrid) Morris et al., Hum Mol Genet 2003
• IRef Hprd Interaction: DISC1 — ATF4 (in vivo) Morris et al., Hum Mol Genet 2003
• IRef Hprd Interaction: DISC1 — ATF4 (two hybrid) Morris et al., Hum Mol Genet 2003
• IRef Intact Interaction: ATF4 — DISC1 (physical association, two hybrid) Morris et al., Hum Mol Genet 2003
• IRef Ophid Interaction: ATF4 — DISC1 (aggregation, interologs mapping) Brown et al., Bioinformatics 2005
• IRef Ophid Interaction: ATF4 — DISC1 (aggregation, confirmational text mining) Morris et al., Hum Mol Genet 2003

Text-mined interactions from Literome

Malavasi et al., Hum Mol Genet 2012 (Rhabdomyosarcoma) : At basal cAMP levels, wild-type DISC1 inhibits the transcriptional activity of ATF4 , an effect that is weakened by both 37W and 607F independently, most likely as a consequence of their defective nuclear targeting
Soda et al., Mol Psychiatry 2013 : We found that the loss of function of either DISC1 or ATF4 increases PDE4D9 transcription, and that the association of DISC1 with the PDE4D9 locus requires ATF4