Yue et al., Carcinogenesis 2008
(Lung Neoplasms) :
Downregulation of Dkk3 activates beta-catenin/TCF-4 signaling in lung cancer
Wang et al., Mol Cell Biol 2008
:
Reduction of DKK3 in control cells with a short hairpin RNA ( shRNA ) increases Notch and beta-catenin/TCF activation, whereas reduction of PLF1 with a shRNA in Msi1 expressing cells inhibits these pathways