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DMP1 — FGF1

Text-mined interactions from Literome

Pereira et al., Bone 2009 (Kidney Failure, Chronic) : Circulating FGF-23 levels are increased in patients with chronic kidney disease ( CKD ) ; however, FGF-23 skeletal expression and its regulation by DMP1 and MEPE have yet to be evaluated
Kyono et al., J Bone Miner Metab 2012 (MAP Kinase Signaling System) : Since Dmp1 plays a central role in osteocyte differentiation and mineral homeostasis, we further analyzed FGF regulation of Dmp1 ... Furthermore, increased extracellular phosphate levels partially inhibited FGF2 induced upregulation of Dmp1 mRNA expression, suggesting a coordinated regulation of Dmp1 expression by FGF signaling and extracellular phosphate ... Collectively, our observations indicate that FGF signaling coordinately regulates mineralization related genes in the osteoblast lineage and that ERK signaling is essential for Dmp1 expression and osteocyte differentiation