Gene interactions and pathways from curated databases and text-mining

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DSC1 — MAPK3

Text-mined interactions from Literome

Pan et al., Biochim Biophys Acta 2013 : DSC concentration-dependently attenuated cell death, lactate dehydrogenase release, intracellular and mitochondrial ROS production, and d? collapse, modulated apoptosis related proteins ( Bcl-2, Bax, caspase-3, p53, and cleaved PARP ) expression, and inhibited phosphorylation of extracellular signal regulated kinase 1/2 in SH-SY5Y cells induced by HO
Liu et al., Eur J Pharmacol 2013 : Signal transduction studies indicated that DSC significantly inhibited LPS induced phosphorylation of Akt, but not c-Jun N-terminal kinase 1/2, p38, or extracellular signal regulated kinase 1/2