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DUT — TP53

Text-mined interactions from Literome

Pugacheva et al., Oncogene 2002 : Here we show that conditional expression of His175 and Trp248 hot-spot p53 mutants in p53 negative mouse 10 ( 1 ) fibroblasts and human SK-OV3 and H1299 tumor cells results in increase in dUTPase gene transcription, an important marker predicting the efficacy of cancer therapy with fluoropyrimidine drugs
Fritzsche et al., Anticancer Drugs 2004 : Furthermore, dUTPase gene expression was not stimulated by mutant p53 , but instead by cellular events that involve DNA synthesis