◀ Back to VEGFA

ECM1 — VEGFA

Text-mined interactions from Literome

Xu et al., American journal of physiology. Renal physiology 2006 : Our data also indicate that simvastatin, via mevalonate depletion, reverses VEGF induced ECM accumulation by preventing RhoA activation
Wang et al., Arterioscler Thromb Vasc Biol 2009 : Depletion of GIT1 by siRNA also significantly inhibited VEGF induced MMP2 activation and extracellular matrix ( ECM ) degradation ... Therefore, GIT1 mediates VEGF induced matrix metalloproteinase ( MMP ) activation and ECM degradation by regulating podosome formation
Xiao et al., Ther Apher Dial 2010 : CTGF expression was increased after stimulation with TGF-beta1, but inhibited using each of the four independent CTGF shRNA constructs ( P < 0.01 ). Moreover, expression of ECM proteins ( FN, col 1, and laminin ) and VEGF were upregulated after incubation with TGF-beta1, but elevated levels of ECM and VEGF induced by TGF-beta1 were significantly inhibited by RNAi ( P < 0.01 ), but not by the empty retroviral vector ( P > 0.05 )
Köhn-Luque et al., PloS one 2011 : In this study, we propose a mathematical model based on the alternative assumption that endodermal VEGF signalling activity, having a paracrine effect on adjacent angioblasts, is mediated by its binding to the extracellular matrix ( ECM )