Gene interactions and pathways from curated databases and text-mining

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EDN1 — TGFB3

Text-mined interactions from Literome

Rodríguez-Pascual et al., Circ Res 2003 : Functional cooperation between Smad proteins and activator protein-1 regulates transforming growth factor-beta mediated induction of endothelin-1 expression
Simonson et al., J Lab Clin Med 1992 : The fact that endothelin secretion is stimulated by cytokines, growth factors, and transforming growth factor beta is consistent with this role
Rodríguez-Pascual et al., J Cardiovasc Pharmacol 2004 : We have analyzed the mechanism by which transforming growth factor-beta increases endothelin-1 expression in vascular endothelial cells ... Transcriptional activation of the endothelin-1 promoter accounted for the transforming growth factor-beta induced increase in endothelin-1 mRNA levels ... Overexpression of the Smad3 isoform strongly potentiates transforming growth factor-beta- induced endothelin-1 promoter activity in a phosphorylation dependent manner ... These results demonstrate that transforming growth factor-beta induces endothelin-1 expression by a functional cooperation between Smads and activator protein-1 through activation of the Smad signaling pathway
Rieder et al., Klin Wochenschr 1991 : In the presence of transforming growth factor beta a dose dependent increase of immunoreactive endothelin release was measured
Schnermann et al., Endocrinology 1996 : Regulation of endothelin production and secretion in cultured collecting duct cells by endogenous transforming growth factor-beta